Psychosis and Telehealth: What Virtual Care Can and Can't Do

Psychosis is a set of symptoms, not a single diagnosis. It describes a period when a person's thinking and perception pull away from shared reality, usually involving hallucinations, delusions, or disorganized thought. It can show up inside schizophrenia, bipolar disorder, severe depression, certain medical conditions, or heavy substance use, and the right response depends on which cause is driving it. Research from NIMH's RAISE program shows that early, coordinated specialty care substantially improves long-term outcomes, and that is where telehealth earns its keep. Video visits keep people connected to psychiatrists and therapists between in-person appointments, especially in areas where specialty programs are hours away. What follows walks through what psychosis actually looks like, how treatment teams are structured, when virtual care fits, and how it pairs with schizophrenia care and bipolar treatment.

What Psychosis Is and How It Starts

Psychosis is not a condition itself, but rather a collection of symptoms that can occur in various mental health conditions. During a psychotic episode, a person's thoughts and perceptions are disrupted, making it difficult to distinguish what is real from what is not. This can be a profoundly disorienting and frightening experience.

Psychotic experiences are more common than many people realize. Studies suggest that mild psychotic experiences occur in approximately 5-8% of the general population, while clinically significant psychotic disorders affect about 3% of people at some point in their lives. With proper treatment, many people who experience psychosis recover well and lead fulfilling lives.

The Neuroscience of Psychosis

Research has identified several neurobiological factors associated with psychosis. Brain imaging studies show alterations in brain structure and function, particularly in the prefrontal cortex, hippocampus, and temporal lobes. Neurotransmitter systems are affected, with dopamine dysregulation playing a central role, particularly in the mesolimbic pathway. Glutamate, the brain's primary excitatory neurotransmitter, also appears to be involved.

Genetic factors contribute significantly to risk for psychotic disorders, though no single gene causes psychosis. Rather, many genes of small effect combine with environmental factors. These environmental risk factors include prenatal complications, early childhood adversity, urban upbringing, migration, cannabis use (especially in adolescence), and social isolation.

The Stress-Vulnerability Model

The stress-vulnerability model helps explain how psychosis develops. According to this model, individuals have varying levels of biological vulnerability to psychosis. When vulnerability is high, less stress is needed to trigger an episode; when vulnerability is lower, more significant stressors may be required. This helps explain why psychosis often first appears during stressful life transitions and why stress management is important in prevention.

Types of Psychotic Experiences

Understanding the different types of psychotic symptoms helps in recognizing them and communicating with healthcare providers:

Hallucinations

Hallucinations are sensory experiences that seem completely real but are created by the mind without external stimuli:

• Auditory hallucinations: The most common type, involving hearing sounds or voices that others don't hear. Voices may be single or multiple, familiar or unfamiliar, kind or critical, and may comment on behavior, give commands, or have conversations.
• Visual hallucinations: Seeing things that aren't there, from shadows or shapes to fully formed images of people or objects.
• Tactile hallucinations: Physical sensations without a physical cause, such as feeling touched, tingling, or insects crawling on the skin.
• Olfactory hallucinations: Smelling things that aren't present.
• Gustatory hallucinations: Tasting things without eating.

Delusions

Delusions are strongly held beliefs that persist despite clear evidence to the contrary. They are not simply unusual beliefs but are typically idiosyncratic and not shared by one's cultural group:

• Persecutory delusions: Belief that one is being watched, followed, harassed, or plotted against. This is the most common type of delusion.
• Grandiose delusions: Belief that one has special powers, talents, wealth, or importance, or is a famous or significant person.
• Referential delusions: Belief that random events, objects, or communications have special personal significance directed at oneself (e.g., believing TV broadcasts contain personal messages).
• Somatic delusions: False beliefs about one's body, such as believing one is infested with parasites or that organs are rotting.
• Delusions of control: Belief that one's thoughts, feelings, or actions are being controlled by outside forces.
• Thought insertion/withdrawal: Belief that thoughts are being placed into or removed from one's mind.
• Erotomanic delusions: Belief that another person, often someone famous, is in love with oneself.
• Nihilistic delusions: Belief that oneself, others, or the world does not exist or is about to end.

Disorganized Thinking and Speech

Psychosis can disrupt the organization of thoughts, which manifests in speech patterns:

• Loose associations: Jumping between topics that seem unconnected to others
• Tangentiality: Responses that are only obliquely related to questions
• Circumstantiality: Taking a very indirect, roundabout path to make a point
• Word salad: Speech that is so disorganized it is nearly incomprehensible
• Neologisms: Making up new words
• Clanging: Choosing words based on sound rather than meaning

Disorganized or Catatonic Behavior

Psychosis can affect behavior in various ways:

• Unpredictable or inappropriate emotional responses
• Difficulty performing goal-directed activities
• Unusual mannerisms or postures
• Catatonia: a range of motor abnormalities including immobility, excessive movement, mutism, or unusual postures

Negative Symptoms

Negative symptoms represent a reduction in normal functions:

• Flat affect: Reduced emotional expression
• Alogia: Poverty of speech
• Avolition: Lack of motivation to initiate activities
• Anhedonia: Inability to experience pleasure
• Asociality: Lack of interest in social interactions

Conditions That Can Involve Psychosis

Psychosis can be a symptom of many different conditions. Proper diagnosis is essential because treatment varies depending on the underlying cause.

Primary Psychotic Disorders

• Schizophrenia: A chronic condition characterized by psychotic symptoms lasting at least six months, often accompanied by negative and cognitive symptoms. See our Schizophrenia & Telehealth Guide.
• Schizoaffective disorder: Combines psychotic symptoms with significant mood episodes (depression or mania). See our Schizoaffective Disorder & Telehealth Guide.
• Brief psychotic disorder: Psychotic symptoms lasting less than one month, often triggered by severe stress, with full return to previous functioning.
• Schizophreniform disorder: Symptoms similar to schizophrenia but lasting between one and six months.
• Delusional disorder: Characterized primarily by delusions without other prominent psychotic symptoms; functioning may remain relatively preserved outside the delusional beliefs.

Mood Disorders with Psychotic Features

• Bipolar disorder with psychotic features: Psychosis can occur during severe manic or depressive episodes. Psychotic symptoms typically resolve when the mood episode is treated. See our Bipolar Disorder Telehealth Guide.
• Major depressive disorder with psychotic features: Severe depression can include psychotic symptoms, often with themes related to guilt, worthlessness, or nihilism.

Substance-Related Psychosis

• Substance-induced psychotic disorder: Psychosis directly caused by intoxication or withdrawal from substances including cannabis, stimulants (methamphetamine, cocaine), hallucinogens, alcohol, and certain prescription medications.
• Cannabis and psychosis: Cannabis use, particularly high-potency products and use during adolescence, is associated with increased risk of developing psychotic disorders.

Medical Conditions

Various medical conditions can cause psychotic symptoms, making medical evaluation essential:

• Neurological conditions (brain tumors, stroke, traumatic brain injury, Parkinson's disease, Huntington's disease)
• Infections affecting the brain (encephalitis, meningitis, HIV)
• Autoimmune conditions (anti-NMDA receptor encephalitis, lupus)
• Endocrine disorders (thyroid dysfunction)
• Vitamin deficiencies (B12, thiamine)
• Metabolic disturbances
• Dementia (Lewy body dementia, Alzheimer's disease)

Other Causes

• Postpartum psychosis: A psychiatric emergency occurring shortly after childbirth, requiring immediate treatment.
• Sleep deprivation: Severe sleep deprivation can trigger psychotic symptoms.
• Severe trauma: In rare cases, extreme trauma can lead to brief psychotic experiences.

Only qualified healthcare professionals can determine the cause of psychotic symptoms through a full evaluation.

The Critical Importance of Early Intervention

Early intervention in psychosis is one of the most important factors in achieving good outcomes. Research consistently shows that the sooner treatment begins, the better the long-term prognosis.

The Prodromal Period

The period before and during a first episode of psychosis, often called the "prodrome," may include subtle changes that precede obvious psychotic symptoms. Recognizing these early warning signs can lead to earlier treatment:

• Difficulty thinking clearly or concentrating
• Suspiciousness or uneasiness around others
• Decline in self-care or personal hygiene
• Spending more time alone than usual
• Strong, inappropriate emotions or lack of emotional expression
• Unusual or exaggerated beliefs
• Hearing, seeing, or sensing things others don't (attenuated perceptual experiences)
• Decline in school or work performance
• New difficulty distinguishing reality from imagination
• Vague, unclear speech patterns
• Sleep disturbances
• Social withdrawal

Why Early Treatment Matters

The Duration of Untreated Psychosis (DUP), the time between when psychotic symptoms first appear and when treatment begins, is one of the strongest predictors of outcome. Shorter DUP is associated with:

• Better response to treatment
• Faster symptom improvement
• Lower relapse rates
• Better long-term functioning
• Improved quality of life
• Better preserved cognitive function
• Reduced family burden

Coordinated Specialty Care (CSC)

The gold standard for first-episode psychosis treatment is Coordinated Specialty Care, also known as First Episode Psychosis (FEP) programs. These evidence-based programs bring several specialists together in one team-based plan, including:

• Case management: Coordination of services and support
• Low-dose medication management: Careful use of antipsychotics, typically at lower doses than used historically
• Individual therapy: Often CBT for psychosis (CBTp)
• Family education and support: Psychoeducation and therapy for family members
• Supported education and employment: Help with school or work goals
• Peer support: Connection with others who have experienced psychosis

Research shows that CSC programs significantly improve outcomes compared to standard treatment. The SAMHSA Early Serious Mental Illness Treatment Locator at findtreatment.gov can help find early psychosis programs in your area.

Care that goes past symptom control

Psychosis is treatable. Many people who experience psychosis recover well with proper care. Treatment typically involves multiple components working together.

Medication Management

Antipsychotic medications are the primary pharmacological treatment for psychosis. They work primarily by modulating dopamine activity in the brain. Online psychiatry services can support ongoing medication management.

Second-Generation (Atypical) Antipsychotics

These are typically the first-line medications for psychosis:

• Risperidone (Risperdal): Effective for positive symptoms; available in long-acting injectable form
• Olanzapine (Zyprexa): Effective but higher risk of weight gain and metabolic effects
• Quetiapine (Seroquel): Often well-tolerated; also has mood-stabilizing properties
• Aripiprazole (Abilify): Partial dopamine agonist with different side effect profile; available as long-acting injectable
• Ziprasidone (Geodon): Lower weight gain risk but requires food for absorption
• Paliperidone (Invega): Active metabolite of risperidone; available in long-acting injectable
• Lurasidone (Latuda): Lower metabolic effects; also FDA-approved for bipolar depression
• Cariprazine (Vraylar): Partial dopamine agonist with efficacy for negative symptoms
• Brexpiprazole (Rexulti): Similar to aripiprazole with potentially less akathisia

First-Generation (Typical) Antipsychotics

Older medications that may be used when other options are not effective or available:

• Haloperidol (Haldol): Highly effective but higher risk of movement side effects
• Fluphenazine (Prolixin): Available in long-acting injectable form
• Chlorpromazine (Thorazine): The first antipsychotic, still sometimes used

Clozapine

Clozapine (Clozaril) is the most effective antipsychotic, reserved for treatment-resistant psychosis (when two other antipsychotics have failed). It requires regular blood monitoring due to risk of agranulocytosis (a serious blood condition) but can be life-changing for those who don't respond to other medications.

Long-Acting Injectables (LAIs)

When remembering a pill every day is the hard part, a long-acting injectable (LAI) can carry the dose instead; depending on the product, the shot is given every two to four weeks or once a month, and a few versions last longer. Injections have to be given in person, so a telehealth prescriber will need a clinic or pharmacy nearby to administer them. Available LAIs include:

• Paliperidone palmitate (monthly and 3-monthly formulations)
• Aripiprazole lauroxil (monthly and 2-monthly)
• Risperidone long-acting injection (every 2 weeks)
• Olanzapine pamoate (every 2-4 weeks)
• Haloperidol decanoate (monthly)
• Fluphenazine decanoate (every 2-4 weeks)

Medication Principles for First-Episode Psychosis

First-episode psychosis typically responds to lower medication doses than chronic psychosis. Treatment principles include:

• Starting with lower doses and titrating slowly
• Choosing medications with better side effect profiles when possible
• Close monitoring for response and side effects
• Patience, as full response may take several weeks
• Avoiding premature medication changes

Psychotherapy Approaches

Therapy is an essential component of psychosis treatment, complementing medication:

Cognitive Behavioral Therapy for Psychosis (CBTp)

CBTp is the most evidence-based psychological treatment for psychosis. It helps individuals:

• Examine and evaluate beliefs related to delusions
• Develop coping strategies for hallucinations (such as voices)
• Reduce distress associated with symptoms
• Improve functioning even when symptoms persist
• Build understanding of the condition
• Reduce risk of relapse

CBTp does not try to eliminate beliefs by force but helps individuals explore alternative explanations and reduce the distress and functional impairment caused by symptoms.

Family Intervention

Family therapy and psychoeducation significantly improve outcomes in psychosis:

• Education about psychosis and its treatment
• Communication skills training
• Problem-solving techniques
• Reducing expressed emotion (criticism and overinvolvement)
• Building a supportive family environment
• Developing crisis plans

Social Skills Training

Structured approaches to improving social functioning:

• Practice of communication skills
• Role-playing social situations
• Feedback and reinforcement
• Graduated exposure to social situations

Cognitive Remediation

Addresses cognitive difficulties common in psychotic disorders:

• Computer-based cognitive training exercises
• Strategy learning for cognitive challenges
• Can improve attention, memory, and executive function

Acceptance and Commitment Therapy (ACT)

Helps individuals accept difficult experiences while committing to valued actions, which can be helpful for those with persistent symptoms.

AVATAR Therapy

An innovative approach for voice hearers that involves creating a computerized avatar representing the voice, then engaging in dialogues to change the relationship with the voice.

Psychosocial Rehabilitation

Treatment extends beyond symptom management:

• Supported employment (IPS model): Evidence-based supported employment helps people find competitive jobs matching their preferences
• Supported education: Support for pursuing educational goals
• Housing support: Assistance with finding and maintaining stable housing
• Case management: Coordination of services and practical support
• Peer support: Connection with others with lived experience of psychosis
• Assertive Community Treatment (ACT): Intensive, team-based community support for those with high needs

Role of Telehealth in Psychosis Care

While active psychosis typically requires in-person care, telehealth can support treatment in several important ways during stable periods and alongside other care.

Appropriate Uses of Telehealth for Psychosis

• Follow-up appointments: Once stable, routine check-ins with psychiatrists and therapists can be conducted via video
• Medication monitoring: Regular reviews of medication effectiveness and side effects
• Family sessions: Include family members in treatment regardless of geographic location
• Early intervention: Quick access to providers when warning signs emerge, potentially preventing full relapse
• Care coordination: Communication between treatment team members
• Psychoeducation: Learning about the condition and recovery
• Ongoing CBTp: Therapy sessions when clinically appropriate
• Support groups: Virtual peer support connections
• Reducing barriers: Overcoming transportation, mobility, and geographic access issues

When In-Person Care Is Necessary

• During active psychotic episodes
• Initial evaluation and diagnosis
• When safety is a concern
• Significant medication changes, especially initiating treatment
• When symptoms interfere with effective virtual communication
• Crisis situations
• When physical examination is needed
• Injection of long-acting antipsychotics

Research on Telehealth for Psychosis

Growing evidence supports telehealth use in psychosis care. Studies have shown:

• Telepsychiatry achieves comparable outcomes to in-person care for stable patients
• High patient and family satisfaction with telehealth services
• Improved access, particularly in rural areas
• Effective delivery of CBTp via video
• Successful family interventions via telehealth

Telehealth-Specific Considerations for Psychosis

• Technology concerns: Some individuals may have paranoid thoughts about technology that need to be addressed
• Privacy: Setting up a private, safe space for appointments
• Crisis protocols: Clear plans for what to do if symptoms worsen
• Support person involvement: Having trusted people available when helpful
• Hybrid approaches: Combining telehealth with periodic in-person visits
• Technical support: Assistance with video conferencing for those unfamiliar with technology

Finding Specialists and Resources

Finding providers with experience treating psychosis is essential for optimal care.

Early Psychosis Programs

Many areas have specialized programs for early psychosis (Coordinated Specialty Care programs). These provide the fullest care for first-episode psychosis:

• SAMHSA Treatment Locator: findtreatment.gov can help find early psychosis programs
• NAVIGATE: A well-known CSC model used in many programs
• OnTrackNY: New York State's early psychosis program
• EASA (Early Assessment and Support Alliance): Programs in Oregon and other states

Online Psychiatry Services

Find care without a sales page: If this may be a first episode, early care matters, and FindTreatment.gov can show programs near you that you can call today. SAMHSA’s National Helpline (1-800-662-4357) offers free referrals 24/7, and the 988 Lifeline can help if anyone is at risk.

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• Talkiatry - In-network psychiatry with experienced providers
• BetterHelp insurance (offered through UpLift) - Medication management and therapy, in network with many plans

Note: Not all telehealth platforms accept patients with psychotic disorders. Always verify provider experience with your specific concerns. Some may require documentation of existing diagnosis or initial in-person evaluation.

Academic Medical Centers

University hospitals often have specialized psychosis clinics and may offer telepsychiatry. Contact the psychiatry department to inquire about services.

Community Mental Health Centers

Community mental health centers specialize in serious mental illness and have expanded telehealth services. They often offer psychiatry, therapy, case management, and peer support, frequently with sliding-scale fees.

Support Organizations

• NAMI (National Alliance on Mental Illness): Education, support groups, and resources at nami.org or 1-800-950-NAMI
• Schizophrenia and Psychosis Action Alliance: Advocacy and community support at sczaction.org
• Hearing Voices Network: Peer support for voice hearers at hearing-voices.org
• EASA (Early Assessment and Support Alliance): Early psychosis resources at easacommunity.org
• Mental Health America: Screening and resources at mhanational.org

Medication Management via Telehealth

Ongoing medication management for psychosis can be conducted effectively via telehealth for stable patients.

What to Expect in Telehealth Medication Appointments

• Discussion of current symptoms, including any hallucinations or unusual thoughts
• Assessment of medication effectiveness
• Review of medication adherence and any barriers
• Monitoring for side effects through conversation and visual observation
• Discussion of sleep, appetite, energy, and daily functioning
• Planning for necessary laboratory work
• Prescription adjustments as needed

Monitoring Requirements

Antipsychotic medications require regular monitoring:

• Metabolic monitoring: Weight, blood sugar, cholesterol (especially important for olanzapine, clozapine)
• Movement assessments: Checking for medication-induced movement disorders
• Cardiovascular: Blood pressure, heart rate; ECG for some medications
• Clozapine monitoring: Mandatory white blood cell counts
• Prolactin: For medications that raise prolactin levels

Lab work is done at local facilities, with results reviewed during telehealth appointments.

Long-Acting Injectable Coordination

If receiving long-acting injectable antipsychotics, injections are administered in person at a clinic, pharmacy, or by a visiting nurse. Telehealth can be used for the psychiatric consultations that monitor response and determine dosing.

If You're Experiencing Symptoms

If you're noticing changes in your thinking or perception that concern you:

What to Do

• Talk to someone you trust: Share what you're experiencing with a family member, friend, or someone you feel safe with
• Reach out to a professional: Contact a mental health professional or your doctor. Many offer telehealth appointments for initial consultations.
• Remember you're not alone: Experiencing these symptoms doesn't mean you're "going crazy"; many people experience psychosis and recover well
• Seek help early: Early intervention leads to better outcomes
• Treatment works: Effective treatments are available for most people

What Not to Do

• Don't isolate yourself
• Don't use alcohol or drugs to cope: they can worsen symptoms
• Don't assume it will just go away on its own
• Don't be afraid to ask for help

Managing While Awaiting Treatment

• Maintain regular sleep patterns
• Avoid substances
• Stay connected to supportive people
• Reduce stress where possible
• Engage in calming activities
• Keep a routine

For Family Members and Caregivers

If you're concerned about a loved one, your involvement can make a significant positive difference in their recovery.

How to Help

• Express concern calmly: Approach conversations with care and without judgment
• Listen: Hear their experiences, even if they seem unusual to you
• Don't argue about reality: Arguing about whether hallucinations or delusions are "real" is usually unproductive. Instead, acknowledge their distress and focus on how they're feeling.
• Encourage professional evaluation: Without being forceful, help them connect with mental health services
• Learn about psychosis: Education helps you understand their experience and provide better support
• Participate in treatment: Attend family therapy and education sessions, many available via telehealth
• Connect with support: Join groups like NAMI for families
• Have a crisis plan: Know what to do if symptoms worsen significantly
• Take care of yourself: Caregiver burnout is real. Maintain your own wellbeing and seek support when needed.

Creating a Supportive Environment

• Maintain calm, low-stress atmosphere
• Reduce criticism and emotional intensity
• Provide structure and routine
• Support medication adherence without nagging
• Encourage healthy habits (sleep, nutrition, avoiding substances)
• Maintain appropriate expectations
• Celebrate progress, even small steps

Recognizing Warning Signs

Learn your loved one's personal early warning signs that may indicate symptoms are returning or worsening:

• Changes in sleep patterns
• Increased isolation or social withdrawal
• Neglecting hygiene or self-care
• Unusual statements or suspiciousness
• Appearing to respond to things you don't perceive
• Increased agitation or irritability
• Changes in eating patterns
• Medication non-adherence

Resources for Families

• NAMI Family-to-Family: 8-session educational program for families, now available virtually
• NAMI Family Support Groups: Peer-led support groups, in-person and virtual
• Family Connections: NAMI program for families of people with borderline personality features
• Local family support services: Many communities have support for families of those with serious mental illness

Recovery and Long-Term Outlook

Recovery from psychosis is possible. With proper treatment and support, many people lead full, meaningful lives.

What Recovery Can Look Like

• Symptom reduction or remission
• Improved daily functioning
• Return to work, school, or other meaningful activities
• Rebuilding and maintaining relationships
• Increased independence
• Better quality of life
• Personal growth and resilience

Keys to Recovery

• Early and consistent treatment: Starting treatment early and staying engaged with care
• Medication adherence: Taking medications as prescribed; discussing concerns with your doctor rather than stopping independently
• Learning warning signs: Knowing your personal early warning signs and having a plan
• Support network: Building connections with understanding people
• Healthy lifestyle: Regular sleep, avoiding substances, managing stress
• Meaningful activities: Engaging in work, education, hobbies, or volunteering
• Self-advocacy: Learning to speak up for your needs
• Hope: Maintaining hope and setting goals for the future

Relapse Prevention

• Know your early warning signs
• Stay connected with treatment providers
• Take medications consistently
• Avoid substances
• Manage stress
• Maintain regular sleep
• Have a crisis plan in place
• Keep your support network informed

Crisis Resources and Emergency Planning

Having a crisis plan is essential for anyone experiencing psychosis or at risk of psychotic episodes.

Components of a Crisis Plan

• Personal early warning signs that symptoms may be returning
• Coping strategies that have helped
• Triggers to avoid
• List of medications, doses, and prescribing doctors
• Treatment provider contact information
• Emergency contacts (family, friends)
• Preferred hospital if needed
• What helps and doesn't help during crises
• Advance directives for psychiatric care

When to Seek Emergency Help

• Thoughts of suicide or self-harm
• Thoughts of harming others
• Inability to care for basic needs
• Complete loss of contact with reality
• Dangerous behavior
• Severe medication side effects

Crisis Resources

• 988 Suicide and Crisis Lifeline: Call or text 988 for 24/7 support
• Crisis Text Line: Text HOME to 741741
• Local emergency services: Call 911 for immediate danger
• Local psychiatric emergency services: Many areas have specialized psychiatric crisis teams or psychiatric emergency rooms
• NAMI Helpline: 1-800-950-NAMI (6264) for information and referrals

Next guides to read after psychosis care

• Schizophrenia & Telehealth Support
• Schizoaffective Disorder & Telehealth
• Bipolar Disorder Telehealth Options
• Online Psychiatry Services Compared
• Telehealth Medication Management Compared
• Emergencies & Telehealth

Sources

• UpLift acquires Minded (November 15, 2023)
• Teladoc Health acquires UpLift (April 30, 2025)
• UpLift’s site, now under the BetterHelp name (checked October 22, 2026)

Who researched and edited this psychosis care guide

Everything in this psychosis care guide was written and edited by Paul Paradis, the founder and editor of Telehealth Navigator, whose background includes more than two years inside a forensic mental health hospital setting and a personal and family life that mental health runs through. His method is to read the source material most readers don’t have time for, which means APA and NIMH guidance, CMS telehealth policy, and SAMHSA program documents, all of it rewritten here in plain English with links back to each original so you can verify it yourself. Paul is not a licensed clinician, and nothing in this psychosis care guide is medical advice, and the full process for how each guide is researched, reviewed, and updated is described in our editorial standards.